ID
Name
Class
Organism
Assay Summary
1
kalata B1
Cyclotide
Viola odorata Oldenlandia affinis Viola tricolor Hybanthus enneaspermus Viola baoshanensis Viola yedoensis Viola philippica Viola sumatrana Miq
Resistance to enzymatic digest shown for kalata B1 and acyclic permutants. Reduced protein was susceptible. [...] G6A and E7A mutants of kalata B1 were completely impervious to enzymatic digestion by the three endoproteinases trypsin, chymotrypsin, and proteinase K, as was the prototypic cyclotide kalata B1. [...]
18
kalata b1-5
Cyclotide
Synthetic
Resistance to enzymatic digest shown for kalata B1 and acyclic permutants. Reduced protein was susceptible. [...]
22
des(24-28)kB1
Cyclotide
Synthetic
Resistance to enzymatic digest shown for kalata B1 and acyclic permutants. Reduced protein was susceptible. [...] Resistance to enzymatic digest shown for kalata B1 and acyclic permutants. Reduced protein was susceptible. [...]
81
SFTI-1
BBI-like trypsin inhibitor
Helianthus annus Helianthus exilis Helianthus tuberosus Helianthus porteri Helianthus praecox subsp. praecox Helianthus schweinitzii
Bifunctional analogues of SFTI-1 found to be resistant to hydrolysis by trypsin. [...]
82
N-SFTI-1-C
BBI-like trypsin inhibitor
Synthetic
Susceptibility of SFTI-1 analogues to cleavage by chymotrypsin and tryspin. [...]
95
BiKK
BBI-like trypsin inhibitor
Synthetic
Bifunctional analogues of SFTI-1 found to be resistant to hydrolysis by trypsin. [...]
96
BiKF
BBI-like trypsin inhibitor
Synthetic
Bifunctional analogues of SFTI-1 found to be resistant to hydrolysis by trypsin. [...]
99
[Nlys5]SFTI-1
BBI-like trypsin inhibitor
Synthetic
Susceptibility of SFTI-1 analogues to cleavage by chymotrypsin and tryspin. [...]
100
[Nphe5]SFTI-1
BBI-like trypsin inhibitor
Synthetic
Susceptibility of SFTI-1 analogues to cleavage by chymotrypsin and tryspin. [...]
170
cycloviolacin O13
Cyclotide
Viola odorata Hybanthus enneaspermus Viola baoshanensis Viola uliginosa Viola arcuata Viola austrosinensis
Cycloviolacin O13, O14, O16 and O24 were tested for their stability against proteolytic degradation by pepsin, trypsin and thermolysin.No degradation by proteases was observed for any of the cyclotides tested following 6 hours of incubation with enzymes, while the linear control peptide was completely degraded in less than 5 minutes. [...]
172
violacin A
Cyclotide
Viola odorata Psychotria leptothyrsa
violacin A was impervious to digestion by the endopeptidases trypsin and thermolysin following incubation for 6 h [...]
174
cycloviolacin O14
Cyclotide
Viola odorata
Cycloviolacin O13, O14, O16 and O24 were tested for their stability against proteolytic degradation by pepsin, trypsin and thermolysin.No degradation by proteases was observed for any of the cyclotides tested following 6 hours of incubation with enzymes, while the linear control peptide was completely degraded in less than 5 minutes. [...]
176
cycloviolacin O16
Cyclotide
Viola odorata
Cycloviolacin O13, O14, O16 and O24 were tested for their stability against proteolytic degradation by pepsin, trypsin and thermolysin.No degradation by proteases was observed for any of the cyclotides tested following 6 hours of incubation with enzymes, while the linear control peptide was completely degraded in less than 5 minutes. [...]
184
cycloviolacin O24
Cyclotide
Viola odorata
Cycloviolacin O13, O14, O16 and O24 were tested for their stability against proteolytic degradation by pepsin, trypsin and thermolysin.No degradation by proteases was observed for any of the cyclotides tested following 6 hours of incubation with enzymes, while the linear control peptide was completely degraded in less than 5 minutes. [...]
458
[G6A]kalata B1
Cyclotide
Synthetic
G6A and E7A mutants of kalata B1 were completely impervious to enzymatic digestion by the three endoproteinases trypsin, chymotrypsin, and proteinase K, as was the prototypic cyclotide kalata B1. [...]
459
[E7A]kalata B1
Cyclotide
Synthetic
G6A and E7A mutants of kalata B1 were completely impervious to enzymatic digestion by the three endoproteinases trypsin, chymotrypsin, and proteinase K, as was the prototypic cyclotide kalata B1. [...]
1293
MCo-AT1-7
Squash trypsin inhibitor
Synthetic
MCo-AT1-7 showed high stability in human serum, which was more stable than AT1-7 and linear MCo-AT1-7. MCo-AT1-7 was able to increase the intracellular concentration of NO as AT1-7 but not MCOTI-II. [...]