Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond(65) Structure Card

General Information
Name Co-complex structure of bovine trypsin with a modified Bowman-Birk inhibitor (PtA)SFTI-1(1,14), that was 1,4-disubstituted with a 1,2,3- trizol to mimic a trans amide bond
Class BBI-like trypsin inhibitor
Organism Synthetic
Notes Resolution: 1.55 R-Free: 0.22
Type XRAY

References
Tischler,M., Nasu,D., Empting,M., Schmelz,S., Heinz,D.W., Rottmann,P., Kolmar,H., Buntkowsky,G., Tietze,D. and Avrutina,O. (2012) Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations. Angew. Chem. Int. Ed. Engl. 51:3708-3712

Cross-references
Protein SFTI-1(1,14) [P8,P9PtA]
Links PDB 4ABI

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