oRTD-1(88) Protein Card

General Information
Name oRTD-1
Sequence GFCRCLCRRGVCRCICTR
Class Primate
Average Mass 2099.58
Monoisotopic Mass 2097.93
m/z M+H 2098.94
ProteinType Acyclic permutant
Parent RTD-1
Organism Synthetic
Notes Open chain analogue of RTD-1
Cyclic No

Assay
Membrane Binding Assay
The cyclic antimicrobial peptide RTD-1 induces stabilized lipid-peptide domains more efficiently than its open-chain analogue [...]Abuja PM et al. (2004) FEBS Lett 566:301-6
Anti-bacterial
RTD-1-3 shown to possess anti-bacterial activity [...]Tran D et al. (2002) J Biol Chem 277:3079-84

References
Tang YQ, Yuan J, Osapay G, Osapay K, Tran D, Miller CJ, Ouellette AJ, Selsted ME (1999) A cyclic antimicrobial peptide produced in primate leukocytes by the ligation of two truncated alpha-defensins. Science 286:498-502
Abuja PM, Zenz A, Trabi M, Craik DJ, Lohner K (2004) The cyclic antimicrobial peptide RTD-1 induces stabilized lipid-peptide domains more efficiently than its open-chain analogue. FEBS Lett 566:301-6

Cross-references
Nucleic acids
Structure
Links

Tools