(104) Assay Card

General Information
Summary kalata B1 induces disruption of the microvilli, blebbing, swelling, and ultimately rupture of the cells of the gut epithelium
Condition gut of larvae after consumption of kalata B1 was examined by light, scanning, and transmission electron microscopy
Result kalata B1 induces disruption of the microvilli, blebbing, swelling, and ultimately rupture of the cells of the gut epithelium
AssayType Insecticidal

References
Barbeta BL, Marshall AT, Gillon AD, Craik DJ, Anderson MA (2008) Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae Proc Natl Acad Sci U S A 105:1221-1225

Cross-references
Proteins Assayed kalata B1